Erna
Enhancer RNAs (eRNAs) represent a class of relatively long non-coding RNA molecules (50-2000 nucleotides) transcribed from the DNA sequence of enhancer regions. In this review, we discuss eRNA production, characteristics, functions and mechanics. eRNAs can determine chromatin accessibility, histone modification and gene expression by constructing a ‘chromatin loop’, thereby bringing enhancers to their target gene. eRNA can also be involved in the phase separation with enhancers and other proteins ... Leading the charge in the RNA revolution is a class of ncRNAs that are synthesized at active enhancers, called enhancer RNAs (eRNAs). Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from the enhancer. Although critical roles of eRNA in gene transcription control have been increasingly realized, the systemic... Find the latest Ernexa Therapeutics Inc. (ERNA) stock quote, history, news and other vital information to help you with your stock trading and investing.
Enhancer RNAs, or eRNAs, are short non-coding RNA molecules that are transcribed from the loci of enhancers. They are involved in the regulation of gene transcription and can be a therapeutic... Enhancer RNA (eRNA) is a type of transcribed RNA from distal enhancers, which plays key roles in transcription regulatory circuitry to mediate the activation of target gene. The eRNA ‘Details’ section provides comprehensive annotation for eRNAs, including eRNA ID, genome location, size, bidirectional genome location and detailed (epi)genetic information in eRNA regions (Figure 2D). Here, we review the current knowledge of the characteristics of eRNAs, the molecular mechanisms of eRNAs action, as well as diseases related to dysregulation of eRNAs. Keywords: Enhancer RNAs, Enhancers, Gene transcription, Associated diseases.
